8 (E),10 (E),12 (Z) -Octadecatrienoic Acid - CAS 5204-87-5

8 (E),10 (E),12 (Z) -Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28 (E),10 (E),12 (Z) -Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland microsomes (IC50= 31 μM) .4

Apoptosis, Others

Apoptosis, Others

5112

C18H30O2

278.436

CCCCC\C=C/C=C/C=C/CCCCCCC(O)=O

-20°C

Ice Packs

Small Compound