8-NBD-cGMP - CAS 115993-88-9

8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate (cGMP), acting as an effective membrane-permeable fluorescent activator for cGMP-dependent protein kinase isozymes I α and I β. This compound exhibits negligible fluorescence in aqueous solutions, but emits intense fluorescence in hydrophobic environments (such as hydrophobic protein binding sites) .

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115993-88-9

C18H18N9O10PS

583.43

O=C(N=C(N1)N)C2=C1N([C@H]3[C@@H]([C@@]4([H])[C@](COP(O)(O4)=O)([H])O3)O)C(SCCNC5=CC=C([N+]([O-])=O)C6=NON=C56)=N2

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