8-pCPT-cGMP-AM - CAS 272445-72-4

8-pCPT-cGMP-AM (8- (4-Chlorophenylthio) -cGMP-AM) is a highly membrane-permeable prodrug of the PKG agonist 8-pCPT-cGMP, designed to enhance membrane permeability of cGMP. It is converted into its active form within the cell via esterase hydrolysis, thus activating PKG. This compound is utilized to investigate the role of cGMP signaling in neural plasticity and memory formation.

PKA

Tyrosine Kinase/Adaptors

272445-72-4

C19H19ClN5O9PS

559.87

S(C=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(OCOC(C)=O)(=O)O4)[H])[H])C5=CC=C(Cl)C=C5

-20°C

Ice Packs

Small Compound