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Molfinity

8 (S) -HETE - CAS 98462-03-4

8 (S) -HETE - CAS 98462-03-4

SKU:MF-0043095-01

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  • Bioactivity

    8 (S) -HETE, a major lipoxygenase product in PMA-treated murine epidermis, activates mouse keratinocyte protein kinase C with an IC50 of 100 μM and selectively activates PPARα at concentrations as low as 0.3 μM. The stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

  • Target

    Others, PPAR

  • Related Pathways

    Others, Metabolism, DNA Damage/DNA Repair

  • CAS Number

    98462-03-4

  • Molecular Formula

    C20H32O3

  • Molecular Weight

    320.47

  • SMILES

    [C@H](C/C=C\CCCC(O)=O)(/C=C/C=C\C/C=C\CCCCC)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound