8alpha-Tigloyloxyhirsutinolide 13-O-acetate - CAS 83182-58-5

8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has anti-cancer activity, it is active against both cancer cell lines (IC50 = 3.50 microM for HT29 and IC50 = 4.27 microM for HepG2) .

STAT, MAO, Reactive Oxygen Species, c-Myc, Bcl-2 Family, Pyroptosis, Cytochromes P450, NADPH-oxidase, Apoptosis, ROS

Cell Cycle/Checkpoint, Neuroscience, JAK/STAT signaling, Immunology/Inflammation, Stem Cells, NF-κB, Apoptosis, Metabolism

83119

C22H28O8

420.45

C\C=C(/C)C(=O)O[C@H]1C[C@@H](C)[C@]2(O)CC[C@@](C)(O2)\C=C2OC(=O)C(COC(C)=O)=C1\2

-20°C

Ice Packs

Natural Product