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9-Decyn-1-ol - CAS 17643-36-6
9-Decyn-1-ol - CAS 17643-36-6
SKU:MF-0034378-01
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Product Details
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Bioactivity
9-Decyn-1-ol is an alkyl/ether-based PROTAC linker used in synthesizing PROTACs, acting as a conjugation agent to combine GDC-0068 and Lenalidomide to form INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].
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Target
PROTAC Linker, Others
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Related Pathways
Others, PROTAC
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CAS Number
17601
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Molecular Formula
C10H18O
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Molecular Weight
154.25
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SMILES
C(CCCC#C)CCCCO
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC