(9R) -RO7185876 - CAS 2226077-86-5

(9R) -RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.

Gamma-secretase, Beta Amyloid

Stem Cells, Proteases/Proteasome, Neuroscience

2225986

C25H28F3N7

483.532

N(C=1N=C2[C@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H]

-20°C

Ice Packs

Small Compound