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Molfinity

A 1070722 - CAS 1384424-80-9

A 1070722 - CAS 1384424-80-9

MF-0004267-01

$38.41 USD
$38.41 USD
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Product Details

  • Bioactivity

    A 1070722 is a potent and selective GSK-3 inhibitor, exhibiting high affinity for both GSK-3α (Ki = 0.6 nM) and GSK-3β (Ki = 0.6 nM) . It can penetrate the blood-brain barrier (BBB) and accumulate in brain regions, indicating potential use as a PET radiotracer for quantifying GSK-3 in the brain.

  • Target

    GSK-3

  • Related Pathways

    PI3K/Akt/mTOR signaling, Stem Cells

  • CAS Number

    1384335

  • Purity

    0.999

  • Molecular Formula

    C17H13F3N4O2

  • Molecular Weight

    362.31

  • SMILES

    COc1ccc2c(NC(=O)Nc3cccc(n3)C(F)(F)F)ccnc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound