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Molfinity

A-1155463 - CAS 1235034-55-5

A-1155463 - CAS 1235034-55-5

MF-0015614-01

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Product Details

  • Bioactivity

    A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W (Ki=19 nM) and MCL-1 (Ki>440 nM) .

  • Target

    Bcl-2 Family

  • Related Pathways

    Apoptosis

  • CAS Number

    1234974

  • Purity

    0.99

  • Molecular Formula

    C35H32FN5O4S2

  • Molecular Weight

    669.79

  • SMILES

    C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide