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A-395 - CAS 2089148-72-9
A-395 - CAS 2089148-72-9
SKU:MF-0004270-01
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Product Details
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Bioactivity
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM) .
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Target
Histone Methyltransferase
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Related Pathways
Chromatin/Epigenetic
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CAS Number
2089067
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Purity
0.9843
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Molecular Formula
C26H35FN4O2S
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Molecular Weight
486.65
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SMILES
CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(C)(=O)=O)C1CCc2cccc(F)c12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound