Molfinity

A-674563 - CAS 552325-73-2

SKU:MF-0016254-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO)

Product Details

Bioactivity
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
Target
ERK, GSK-3, Akt, PKA, CDK
Related Pathways
Stem Cells, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, MAPK
CAS Number
552250
Purity
0.9921
Molecular Formula
C22H22N4O
Molecular Weight
358.44
SMILES
Cl.Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound