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A-740003 - CAS 861393-28-4
A-740003 - CAS 861393-28-4
SKU:MF-0051852-01
Regular price
$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human) . It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice.
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Target
P2X Receptor
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Related Pathways
Neuroscience, Membrane transporter/Ion channel
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CAS Number
861361
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Purity
0.9968
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Molecular Formula
C26H30N6O3
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Molecular Weight
474.55
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SMILES
COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound