A-770041 - CAS 869748-10-7

A-770041 is an orally active and selective Lck inhibitor that inhibits concanavalin A-stimulated IL-2 production in whole blood and prevents cardiac allograft rejection. A-770041 reduces pulmonary fibrosis by inhibiting TGF-β production in regulatory T cells.

Src

Tyrosine Kinase/Adaptors, Angiogenesis

869731

0.9986

C34H39N9O3

621.73

NC1=C2C(=NN(C2=NC=N1)[C@H]3CC[C@@H](CC3)N4CCN(C(C)=O)CC4)C5=CC(OC)=C(NC(=O)C6=CC=7C(N6C)=CC=CC7)C=C5

-20°C

Ice Packs

Small Compound