A 784168 - CAS 824982-41-4

A-784168, a potent and orally active inhibitor of vanilloid receptor type 1 (TRPV1), acts on a ligand-gated nonselective cation channel pivotal in integrating pain stimuli including endogenous lipids, capsaicin, heat, and low pH. It demonstrates commendable central nervous system (CNS) penetration upon oral administration [1].

TRP/TRPV Channel, Others

Membrane transporter/Ion channel, Others

824937

C19H15F6N3O3S

479.4

C(F)(F)(F)C1=C(N=CC=C1)N2CCC(C(NC3=CC=C(S(C(F)(F)F)(=O)=O)C=C3)=O)=CC2

-20°C

Ice Packs

Small Compound