A 80915A - CAS 127875-60-9

A 80915A is A semi-naphthoquinone antibiotic from Streptomyces aculeolatus. It is a potent inhibitor of gastric (H (+) -K+) -ATPase. Inhibition by A80915A is dependent on the conformation of gastric (H (+) -K+) -ATPase, potassium slows the rate of inhibition by converting the enzyme to a conformation where the drug binding site is not as accessible.

Others, Proton pump, ATPase

Others, Membrane transporter/Ion channel

127806

C26H31Cl3O5

529.88

Cc1c(O)cc2C(=O)C3(CC4C(=C)CCC(Cl)C4(C)C)OC(C)(C)C(Cl)CC3(Cl)C(=O)c2c1O

-20°C

Ice Packs

Small Compound