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Molfinity

A 83-01 - CAS 909910-43-6

A 83-01 - CAS 909910-43-6

MF-0036567-01

$48.87 USD
$33.80 USD $48.87 USD
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Product Details

  • Bioactivity

    A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM) . A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures.

  • Target

    ALK, TGF-beta/Smad

  • Related Pathways

    Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors

  • CAS Number

    909910-43-6

  • Purity

    0.9876

  • Molecular Formula

    C25H19N5S

  • Molecular Weight

    421.52

  • SMILES

    Cc1cccc(n1)-c1nn(cc1-c1ccnc2ccccc12)C(=S)Nc1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound