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A 83-01 sodium salt - CAS 2828431-89-4

A 83-01 sodium salt - CAS 2828431-89-4

SKU:MF-0004549

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  • Bioactivity

    A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1].

  • Target

    ALK, TGF-beta/Smad

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells

  • CAS Number

    2828338

  • Molecular Formula

    C25H19N5NaS+

  • Molecular Weight

    444.51

  • SMILES

    S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5.[Na+]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound