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Molfinity

A-9758 - CAS 2055271-22-0

A-9758 - CAS 2055271-22-0

MF-0004276-01

$2,673.72 USD
$1,943.50 USD $2,673.72 USD
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Product Details

  • Bioactivity

    A-9758 is a RORγ ligand and selective RORγt inverse agonist (IC50: 5 nM) that effectively suppresses IL-17A release, Th17 differentiation, and Th17 effector function, significantly attenuating IL-23 driven psoriasiform dermatitis.

  • Target

    ROR, Interleukin

  • Related Pathways

    Metabolism, Immunology/Inflammation

  • CAS Number

    2055271-22-0

  • Molecular Formula

    C25H23Cl2F3N2O3

  • Molecular Weight

    527.36

  • SMILES

    CN1C=2C(C=C1CC3=C(Cl)C(C(=O)N4CCC(C(O)=O)CC4)=CC=C3Cl)=C(C)C=C(C(F)(F)F)C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound