Aβ aggregation-IN-1 - CAS 352525-91-8

Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.

Beta Amyloid

Neuroscience

352426

C9H8BF3O2

215.965

C(F)(F)(F)C1=CC=C(/C=C/B(O)O)C=C1

-20°C

Ice Packs

Small Compound