αA-Conotoxin PIVA - CAS 171439-59-1

αA-Conotoxin PIVA serves as a selective inhibitor of mouse muscle nicotinic acetylcholine receptors (nAChRs), demonstrating half-maximal inhibitory concentrations (IC50) of 2.3 nM for adult and 22 nM for fetal mouse muscle nAChRs. The compound is utilized in research related to neurological diseases.

AChR

Neuroscience

171379

C103H150N34O37S6

2648.89

O=C1N2[C@@](C[C@@H](O)C2)(C(=O)N[C@@]3(C(=O)N[C@@H](CO)C(=O)N[C@](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N4[C@](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@H](C(NCC(N[C@@H](CCC(N)=O)C(N)=O)=O)=O)CSSC3)(C[C@@H](O)C4)[H])(CSSC[C@H](NC(CN)=O)C(=O)N[C@]6(CSSC[C@@](C(=O)N[C@H]1CC7=CN=CN7)(NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@]8(N(C(=O)[C@H](CC9=CC=C(O)C=C9)NC(=O)[C@H](CO)NC(=O)CNC6=O)C[C@H](O)C8)[H])[H])[H])[H])[H])[H]

-20°C

Ice Packs

Peptide