A17 - CAS 2568186-47-8

A17, a bile acid analog, exhibits anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory properties. This compound diminishes fatty acid (FA) uptake and enhances FA oxidation by suppressing fatty acid translocase (Cd36) expression and stimulating AMPKα activity. A17 is applicable in NASH research.

AMPK

PI3K/Akt/mTOR signaling, Chromatin/Epigenetic

2568186-47-8

C31H51NO6

533.74

O(C=O)[C@@H]1[C@@]2([C@@]([C@]3(C)[C@](C1)(C[C@H](OC=O)CC3)[H])(CC[C@@]4(C)[C@]2(CC[C@@]4([C@@H](CCC(N[C@@H](C(C)C)CO)=O)C)[H])[H])[H])[H]

-20°C

Ice Packs

Small Compound