A17 peptide - CAS 1140483-31-3

A17 peptide is an Hsp70-targeting peptide. It binds to the ATP-binding domain of Hsp70, specifically inhibiting its chaperone activity. This enhances cellular sensitivity to chemotherapeutic drugs, such as those inducing apoptosis via Cisplatin. A17 peptide is applicable in cancer chemotherapy research, including studies on multiple myeloma.

HSP

Metabolism, Cytoskeletal Signaling

1140483-31-3

C76H105N19O20S

1636.83

C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCCCN)=O)=O)CCCNC(=N)N)(=O)[C@H]3N(C([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@H](CC5=CC=C(O)C=C5)NC([C@@H](NC([C@@H](NC([C@H](CC6=CC=C(O)C=C6)N)=O)CS)=O)C)=O)=O)=O)CO)=O)CCC3

-20°C

Ice Packs

Peptide