A1874 - CAS 2064292-12-0

A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.

Epigenetic Reader Domain, PROTACs

PROTAC, Chromatin/Epigenetic

2064280

0.9952

C58H62Cl3F2N9O7S

1173.59

C(#N)[C@]1([C@H]([C@H](C(NC2=C(OC)C=C(C(NCCOCCOCCOCCNC(C[C@H]3C=4N(C5=C(C(=N3)C6=CC=C(Cl)C=C6)C(C)=C(C)S5)C(C)=NN4)=O)=O)C=C2)=O)N[C@H]1CC(C)(C)C)C7=C(F)C(Cl)=CC=C7)C8=C(F)C=C(Cl)C=C8

-20°C

Ice Packs

PROTAC