A8 peptide - CAS 1140483-17-5

A8 peptide is an Hsp72 antagonist that hinders tumor progression and metastasis by disrupting the Hsp72-TLR2 interaction and subsequent activation of MDSCs, thereby increasing cancer cells' sensitivity to chemotherapeutic agents like cisplatin (Cisplatin-induced apoptosis sensitivity) . A8 peptide is applicable in cancer research.

HSP

Cytoskeletal Signaling, Metabolism

1140483-17-5

C48H66N12O12

1003.11

C([C@@H](C(=O)N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(O)=O)=O)[C@@H](C)O)=O)CCC2)CCCNC(=N)N)=O)CCC1)NC(=O)[C@H]4N(C([C@H](CO)N)=O)CCC4)C=5C=6C(NC5)=CC=CC6

-20°C

Ice Packs

Peptide