AA147 - CAS 393121-74-9

AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.

Others, Reactive Oxygen Species, ROS

Metabolism, Immunology/Inflammation, NF-κB, Others

393038

0.9979

C16H17NO2

255.31

Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1

-20°C

Ice Packs

Small Compound