AAF-CMK (trifluoroacetate salt) - CAS 184901-82-4

Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50 μM.

Others, Proteasome

Others, Proteases/Proteasome, Ubiquitination

184815

C18H23ClF3N3O5

453.84

OC(=O)C(F)(F)F.C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H](Cc1ccccc1)C(=O)CCl

-20°C

Ice Packs

Small Compound