AAK1-IN-5 - CAS 1815613-44-5

AAK1-IN-5 is a potent and specific inhibitor of adaptor protein-2-associated kinase 1 (AAK1), characterized by its ability to penetrate the central nervous system and its oral bioavailability. It displays high selectivity, with an AAK1 inhibitory potency (IC 50) of 1.2 nM, a binding affinity (K i) of 0.05 nM, and an inhibitory potency against cellular AAK1 activity (cell IC 50) of 0.5 nM. AAK1-IN-5 holds promise for investigating neuropathic pain in scientific research [1].

Others, AAK1 (AP2 associated kinase 1)

Others, Neuroscience

1815564

C19H23F4N3O

385.4

C(F)(F)C=1C=C(N=CC1OC[C@@](CC(C)C)(C)N)C=2C=C(C(F)F)N=CC2

-20°C

Ice Packs

Small Compound