AAK1-IN-8 - CAS 2969205-90-9

AAK1-IN-8 (Compound 18) is a broad-spectrum NAK inhibitor. It effectively inhibits AAK1 and GAK with EC50 values of 50 nM and 190 nM, respectively, and prevents the phosphorylation of the AP2-μ2 subunit at threonine 156 (T156) .

Serine/threonin kinase, AAK1 (AP2 associated kinase 1)

Cell Cycle/Checkpoint, Neuroscience, Metabolism

2969106

C24H23N5O3

429.47

O=C(NCC=1C=CC=CC1)C2=CC=C3C=C2OCCOCCN=C4C=CN5N=CC3=C5N4

-20°C

Ice Packs

Small Compound