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Molfinity

AAPK-25 - CAS 2247919-28-2

AAPK-25 - CAS 2247919-28-2

MF-0004281-01

$48.87 USD
$48.87 USD
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Product Details

  • Bioactivity

    AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, causing mitotic delay and arresting cells in prometaphase, followed by increased apoptosis. It targets Aurora-A/-B/-C with Kd values ranging from 23-289 nM.

  • Target

    Apoptosis, Aurora Kinase, PLK

  • Related Pathways

    Cell Cycle/Checkpoint, Chromatin/Epigenetic, Apoptosis

  • CAS Number

    2247889

  • Purity

    0.9779

  • Molecular Formula

    C21H13Cl2N3O2S

  • Molecular Weight

    442.32

  • SMILES

    Clc1ccc(cc1Cl)C(=O)Nc1ccc2cc(ccc2c1)C(=O)Nc1nccs1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound