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AB-452 - CAS 2226178-35-2
AB-452 - CAS 2226178-35-2
SKU:MF-0061550-01
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Product Details
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Bioactivity
AB-452, a dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer that inhibits PAPD5/7 proteins in vitro and demonstrates good in vivo efficacy in a chronic HBV mouse model [1].
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Target
HBV
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Related Pathways
Microbiology/Virology
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CAS Number
2226178-35-2
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Molecular Formula
C21H26N2O6
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Molecular Weight
402.44
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SMILES
[C@@H](C)(C)[C@H]1N2C(C=3C(C1)=CC(OCCCOC)=C(OC)N3)=CC(=O)C(C(O)=O)=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound