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Molfinity

AB8939 - CAS 1974336-09-8

AB8939 - CAS 1974336-09-8

MF-0061567-01

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Product Details

  • Bioactivity

    AB8939 is a potent small-molecule inhibitor of microtubule/tubulin polymerization, exhibiting antitumor activity (with tumor cell proliferation inhibition IC50≤10 nM) . It effectively circumvents resistance mechanisms mediated by P-glycoprotein and myeloperoxidase. AB8939 can induce G2/M phase cell cycle arrest and apoptosis.

  • Target

    Microtubule Associated, Apoptosis

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling

  • CAS Number

    1974336-09-8

  • Molecular Formula

    C22H24N4O3

  • Molecular Weight

    392.451

  • SMILES

    O=C1NCCN1C=2C=CC(=CC2)C=3OC(=NC3)NC4=CC(=CC=C4C)COCC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound