ABCG2-IN-1 - CAS 2559759-40-7

ABCG2-IN-1 (compound K2), an analog of Ko143, is an orally active inhibitor of ABCG2 with an IC50 of 0.13 μM, demonstrating favorable oral pharmacokinetics in mice and showing promise for further research [1].

BCRP

Membrane transporter/Ion channel

2559712

C26H36N4O4

468.59

C(C(C)C)[C@H]1C2=C(C=3C(N2)=CC(OC)=CC3)C[C@@]4(N1C(=O)[C@H](CCC(NC(C)(C)C)=O)NC4=O)[H]

-20°C

Ice Packs

Small Compound