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Abetimus - CAS 167362-48-3
Abetimus - CAS 167362-48-3
SKU:MF-0063988-01
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Product Details
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Bioactivity
Abetimus (LJP 394 free base), an immunosuppressant composed of four double-stranded DNA (dsDNA) oligonucleotides, can crosslink anti-dsDNA antibodies on B cell surfaces and reduce anti-dsDNA antibody levels, offering research potential for systemic lupus erythematosus [1].
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Target
Others, DNA/RNA Synthesis
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Related Pathways
Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
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CAS Number
167362-48-3
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Molecular Formula
C11H18N4O7
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Molecular Weight
318.28
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SMILES
O=C(C1CC([C-](C(C1)=O)C(CC)=O)=O)[O-].[0.5Ca2+].[0.5Ca2+]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound