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Abexinostat - CAS 783355-60-2

Abexinostat - CAS 783355-60-2

SKU:MF-0003494-01

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  • Bioactivity

    PCI-24781 (Abexinostat (PCI24781) ) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.

  • Target

    HDAC

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    783293

  • Purity

    0.9843

  • Molecular Formula

    C21H23N3O5

  • Molecular Weight

    397.42

  • SMILES

    CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound