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ABS-752 - CAS 2761170-84-5
ABS-752 - CAS 2761170-84-5
SKU:MF-0061634-01
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Product Details
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Bioactivity
ABS-752 is an effective and orally active molecular glue degrader targeting GSPT1 and NEK7. It exhibits cytotoxic properties and reduces the protein expression of GSPT1, SALL4, and NEK7. ABS-752 possesses anticancer activity and shows potential for research in hepatocellular carcinoma.
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Target
Molecular Glues, MAPK
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Related Pathways
PROTAC, MAPK
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CAS Number
2761081
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Molecular Formula
C14H14FN3O3
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Molecular Weight
291.28
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SMILES
O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(C=C3C2)CN)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC