ABZI - CAS 2248444-14-4

(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.

STING

Immunology/Inflammation

2248426

C23H24N6O3

432.48

C([C@@H](O)C1=CC=CC=C1)N2C=3C(N=C2NC(=O)C=4N(CC)N=C(C)C4)=CC(C(N)=O)=CC3

-20°C

Ice Packs

Small Compound