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AC-264613 - CAS 1051487-82-1
AC-264613 - CAS 1051487-82-1
SKU:MF-0061677-01
Regular price
$133.06 USD
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$133.06 USD
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Product Details
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Bioactivity
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2) . AC-264613 (AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613 (AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca (2+) mobilization assays, with potencies ranging from 30 to 100 nM.
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Target
Protease-activated Receptor
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Related Pathways
GPCR/G Protein
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CAS Number
1051404
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Molecular Formula
C19H18BrN3O2
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Molecular Weight
400.28
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SMILES
CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound