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Molfinity

AC-264613 - CAS 1051487-82-1

AC-264613 - CAS 1051487-82-1

SKU:MF-0061677-01

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  • Bioactivity

    AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2) . AC-264613 (AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613 (AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca (2+) mobilization assays, with potencies ranging from 30 to 100 nM.

  • Target

    Protease-activated Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    1051404

  • Molecular Formula

    C19H18BrN3O2

  • Molecular Weight

    400.28

  • SMILES

    CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound