AC-73 - CAS 775294-71-8

AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 including Glu64 and Glu73), resulting in inhibition of the CD147/ERK1/2/STAT3/MMP-2 pathway and inhibition of liver cancer cell motility and invasion. AC-73 has antiproliferative activity and induces autophagy in leukemia cells.

Autophagy

Autophagy

775215

0.9936

C21H21NO2

319.4

OC(CNCc1ccc(cc1)-c1ccccc1)c1cccc(O)c1

-20°C

Ice Packs

Small Compound