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Ac-DNLD-CHO - CAS 775289-20-8
Ac-DNLD-CHO - CAS 775289-20-8
SKU:MF-0064057-01
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Product Details
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Bioactivity
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, with IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7 nM, respectively. This compound is utilized in the study of diseases associated with caspase-mediated apoptosis, including neurodegenerative and viral infection diseases [1].
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Target
Caspase
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Related Pathways
Proteases/Proteasome, Apoptosis
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CAS Number
775289-20-8
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Molecular Formula
C20H31N5O10
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Molecular Weight
501.49
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SMILES
[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C=O)=O)CC(C)C)=O)(NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide