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Ac-Exatecan - CAS 2922852-48-8

Ac-Exatecan - CAS 2922852-48-8

MF-0064063-01

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Product Details

  • Bioactivity

    Ac-Exatecan (Ac-DX-8951) is acetylation-modified Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM and antitumor activity.

  • Target

    ADC Cytotoxin, Topoisomerase

  • Related Pathways

    Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

  • CAS Number

    2922796

  • Purity

    0.9709

  • Molecular Formula

    C26H24FN3O5

  • Molecular Weight

    477.48

  • SMILES

    N(C(C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound