Ac-PAL-AMC - CAS 1431362-79-6

Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can quantify the activity of the β1i/LMP2 subunit. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm.

Others, Proteasome

Others, Ubiquitination, Proteases/Proteasome

1431277

C26H34N4O6

498.57

CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C(C)=O)CCC3)C)=O)CC(C)C)=O)=CC2)OC(=O)C1

-20°C

Ice Packs

Small Compound