Ac-RYYRIK-NH2 - CAS 200959-48-4

High affinity ligand for the NOP site (Ki = 1.5 nM) . Antagonizes nociceptin-stimulated GTP binding in rat brain and the chronotropic effect of nociceptin on rat cardiomyocytes. However, displays potent agonist properties in vivo, inhibiting locomotor activity in mice.

Opioid Receptor

GPCR/G Protein, Endocrinology/Hormones, Neuroscience

200907

C44H70N14O9

939.12

[C@@H](CC1=CC=C(O)C=C1)(NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CCCNC(=N)N)NC(C)=O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O

-20°C

Ice Packs

Peptide