Acetohexamide - CAS 968-81-0

Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) with Ki values of 22.9 and 14.2 μM in HEK293 cells transfected with the human receptor and in rat brain, respectively. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.

NADPH, Potassium Channel, Others

Metabolism, Membrane transporter/Ion channel, Others

887

0.9985

C15H20N2O4S

324.4

CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1

-20°C

Ice Packs

Small Compound