Acetylcorynoline - CAS 18797-80-3

1. Acetylcorynoline (O-Acetylcorynoline) has antifungal, anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.

Antifungal

Microbiology/Virology

18714

0.9976

C23H23NO6

409.43

[H][C@]12N(C)Cc3c4OCOc4ccc3[C@@]1(C)[C@H](Cc1cc3OCOc3cc21)OC(C)=O

-20°C

Ice Packs

Natural Product