AChE/BChE-IN-9 - CAS 2761542-55-4

AChE/BChE-IN-9 (Compound 7a) is a potent, orally active inhibitor of AChE and BChE, with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. It also demonstrates effective antioxidant activity (IC50 = 57.35 μM), chelates iron, and modulates amyloid β 1-42 aggregation. Notably, AChE-IN-16 can cross the blood-brain barrier [1].

Others, ROS Kinase, Cholinesterase (ChE)

Others, Neuroscience, Tyrosine Kinase/Adaptors

2761483

C20H19N3O4

365.38

N(C(CNC(/C=C/C1=CC(OC)=C(O)C=C1)=O)=O)C=2C=C3C(=CC2)NC=C3

-20°C

Ice Packs

Small Compound