AChE/BuChE-IN-2 - CAS 1946008-31-6

AChE/BuChE-IN-2 (Compound 5f) is an orally active inhibitor of AChE and BuChE with IC50 values of 0.72 μM and 0.16 μM, respectively, and can cross the BBB. AChE/BuChE-IN-2 shows potent inhibition of self-induced β-amyloid (Aβ) aggregation with an IC50 of 62.52 μM and demonstrates non-competitive inhibition with AChE [1].

Cholinesterase (ChE), Beta Amyloid, Others

Others, Neuroscience

1945971

C20H18N2O2

318.37

C=1(C2=C(N=C(C1)C=3C=C4C(=CC3)OCO4)C=CC=C2)N5CCCC5

-20°C

Ice Packs

Small Compound