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AChE-IN-88 - CAS 2758789-03-4
AChE-IN-88 - CAS 2758789-03-4
SKU:MF-0061899-01
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Product Details
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Bioactivity
AChE-IN-88 (Compound 26) is a novel pyrazine derivative. It is an orally active multi-target ligand for Alzheimer's disease (AD), effectively inhibiting both acetylcholinesterase (AChE) and amyloid-beta (Aβ) aggregation with a pIC50 of 7.16.
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Target
Beta Amyloid, Cholinesterase (ChE)
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Related Pathways
Neuroscience
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CAS Number
2758789-03-4
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Molecular Formula
C27H33FN4O3
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Molecular Weight
480.57
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SMILES
O=C1C=CC(=NN1CCCCCCN(CC=2C=CC=C(F)C2)CC)C=3C=C(C=CC3O)NC(=O)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound