Ack1 inhibitor 1 - CAS 2924415-92-7

Ack1 inhibitor 1 is a potent and selective orally active inhibitor of ACK1 kinase, with an IC50 value of 2.1 nM. It effectively inhibits the phosphorylation of ACK1 and the activation of downstream AKT, demonstrating anti-tumor activity [1].

Akt, ACK1

PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

2924415-92-7

C39H40F3N7O4

727.77

C(N1C=2C(C=C(C1=O)C3=CC(NC(=O)C4=CC(C(F)(F)F)=CC=C4)=CC=C3)=CN=C(NC5=C(OCC)C=C(C=C5)N6CCN(C)CC6)N2)[C@H]7CCCO7

-20°C

Ice Packs

Small Compound