Aclacinomycin A - CAS 57576-44-0

Aclacinomycin A (Aclarubicin) is a novel anthracycline antibiotic isolated from Streptomyces galilei with antitumor activity.Aclacinomycin A is an inhibitor of topoisomerases I and II and inhibits RNA activity.Aclacinomycin A has been used in the study of relapsed leukemia and advanced malignant lymphomas.

DNA/RNA Synthesis, Proteasome, Topoisomerase, Antibiotic

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Ubiquitination, Proteases/Proteasome, Microbiology/Virology

57532

0.9943

C42H53NO15

811.87

C(OC)(=O)[C@@H]1C2=C([C@@H](O[C@H]3C[C@H](N(C)C)[C@H](O[C@H]4C[C@H](O)[C@H](O[C@@H]5O[C@@H](C)C(=O)CC5)[C@H](C)O4)[C@H](C)O3)C[C@@]1(CC)O)C(O)=C6C(=C2)C(=O)C=7C(C6=O)=C(O)C=CC7

-20°C

Ice Packs

Natural Product