Aclerastide - CAS 227803-63-6

Aclerastide is an angiotensin receptor agonist. Administration of Aclerastide reduced fibrosis and scarring in the healing wounds. This action was more pronounced with longer administration of the peptide after injury. The action of this peptide was blocked by the AT receptor antagonist d-Ala7-angiotensin (1-7), which suggests that this receptor is involved in the healing responses to exogenous Aclerastide.

RAAS

Endocrinology/Hormones

227734

C42H64N12O11

913.03

C([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCCC)=O)=O)[C@H](CC)C)=O)(=O)N3[C@H](C(O)=O)CCC3

-20°C

Ice Packs

Peptide